Pharmacologists looked at 2400 drugs to see if any of them could stop cell multiplication in tumours and hence stop their fast growth. Itraconazole,first synthesised in 1980, was found by the researchers at Johns Hopkins University in the USA to have the ability to starve tumour cells of their ability to grow new blood cells. Itraconazole is used in foot anti fungal products especially those for onychomycosis. Other similar experiments found that Zinc Pyrithione (also anti-fungal and anti-bacterial) which is an ingredient of anti dandruff shampoos could keep open defective cell gateways within the brain and allow potassium, a nerve calmer to have an improved flow.
A fashion statement or something to give you sore legs and feet? A derivation of the Italian word ‘Stilo’ which means dagger,Stiletto appeared in the English language in the early 17th century meaning a short dagger with a thick blade. Later in the 17th century it described pointed beards and in the 1950’s a shoe heel. The stiletto heels were very popular in the 50’s and 60’s and have from time to time made a comeback. The high heels not only emphasise a ladies attractive legs, adding some height but can over a period of time give the wearer a painful back, corns and shorten the Tendo Achillies (albeit reversible over time) making wearing low heels or flat shoes very uncomfortable. The pressure on the toes and the nails is enormous in the toe box of the shoe and this increases with heel height. The pressure on the heel is also concentrated in one very small surface area and resulted over the years in many a ‘No Stilletos’ sign in halls or shops with fine wooden floors. So what’s best ladies ? If you want to wear the shoes OK, but like lots of things –in moderation and think of your poor toes !
Now that the 26 miles of the London marathon is over again for another year its time to think about the best footwear to use. You would never run a marathon with a pair of heavy safety shoes on, so appropriate for the job footwear is an essential bit of kit. Unless you have the best of trainers on, your feet and legs you will know all about pain and discomfort. So what helps make a good trainer shoe? Light breathable fabric uppers can help keep the foot cool. Great support from a good quality mid sole with a shock absorbing insole. The heel should also be well cushioned and some trainers have gel pads in this important area. Weight is important too, with some brands being as light as 200g. An often asked question is how often to replace trainers? In general if you are serious about running 6 to 9 months is probably about right, less strenuous use could last a bit longer. Shop around,you don’t have to pay top £, best quality trainers are not always the most expensive !